The U.S. Pharmacopeial Convention (USP) Scientist II Synthetics Laboratory in Hyderabad, India

Scientist II Synthetics Laboratory

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Job Description

This is a non-supervisory position responsible for the synthesis, scale-up, purification and characterization of API impurities on milligram-to-multigram scale. The incumbent in this role will plan and execute diverse synthetic schemes to produce reference materials for supporting organizational business initiatives and RS material production.

Roles and Responsibilities:

  • Responsible for carrying out literature search using various scientific data bases such as SciFinder and Reaxys, and design synthetic schemes to prepare target molecules

  • Responsible for the making project proposals with cost estimate

  • Perform wide range of critical reactions involving air sensitive and moisture sensitive reagents to synthesize desired compounds

  • Optimize reaction conditions and apply purification procedures to produce quality products as per specifications

  • Characterization of compounds based on analytical data such as IR, NMR, Mass Spectra

  • Documentation of experiments conducted and the observation made as per QA guidelines

  • Follow personal and lab safety guidelines

Required Skills

  • M.Sc in Organic chemistry with not less than 4-6 years of work experience in CRO or Pharmaceutical Process R&D, or NCE R&D.

  • Hands on experience in the synthesis, purification and characterization of wide range of organic compounds

  • Expertize in designing synthetic routes for any given target molecule

  • Ability to carry literature search using scientific databases – Scifinder,and Reaxys etc

Required Experience

  • Sound knowledge in Synthetic organic chemistry and excellent troubleshooting skills

  • Track record of producing structurally diverse compounds including heterocycles and macrolides

  • Ability to work in a cross functional team environment

  • Interpretation of Analytical data such as IR, NMR, Mass and HPLC

  • Knowledge of Quality Management systems (ISO9001) or GMP

  • Lab safety awareness and usage of PPE

  • Basic written and verbal communication skills

Job Location

Hyderabad, Andhra Pradesh, India

Position Type


Job Category Scientific