The U.S. Pharmacopeial Convention (USP) Scientist III, Synthetics in Hyderabad, India
Brief Job Overview
The role is engaged in the delivery of USP Reference Standard candidate materials (API Impurities) through development of cost-effective synthetic routes. Candidate should carry literature search using scientific databases and works on design, planning and execution of synthesis of target molecules in mg to multigram/KG scale. Candidate should optimize key reactions and develops scalable process and develop control strategies using PAT. As project team member, ensures the completion of assigned tasks as per timelines, communicates with the team and update on the project progress. They are also responsible for making project reports and technology transfer documents. They should be adherent to QMS and lab safety guidelines. They should possess excellent organizational, communication, and interpersonal skills.
How will YOU create impact here at USP?
Responsible for carrying out literature search and propose and design synthetic routes for target reference materials and for new target molecules respectively.
The candidate should be acquainted with all key name reactions, product identification and purification through various techniques such as crystallization, column chromatography and chemical purification of organic and peptide molecules
Responsible for the synthesis of the products at diverse scales (milligram to multigram)
Experience in handling large scale reactions.
Adept in trouble shooting problems encountered during the reaction sequence
Ability to work on more complicated and creative projects
Conversant with lab safety norms and quality management systems
General Material balance, Process Flow Diagrams (PFD), Recovery of solvents, Selection of equipment etc.,
Characterization of compounds based on IR, NMR, Mass Spectra, Elemental analysis etc.
To execute and completes the projects as per the timelines.
Ensuring that the availability of chemicals, equipment and glass wares etc. for the projects and forward the purchase requisitions.
Periodic check of the assigned equipment to ensure that equipment is in good condition.
To follow QMS of USP
Responsible for review the records and documents
Responsible to ensure the calibrations of the equipment as per the schedule
Maintenance of chemical inventory management system in the lab.
Responsible for maintenance of rejection folder according to synthetic works flow
Who USP is Looking For?
The successful candidate will have a demonstrated understanding of our mission, commitment to excellence through inclusive and equitable behaviors and practices, ability to quickly build credibility with stakeholders, along with the following competencies and experience:
Scientist III – Ph.D (Synthetic Organic Chemistry) from a reputed group with minimum 1-3 years post-doctoral experience in organic and peptide synthesis (Or) M Sc (Organic Chemistry) from a reputed university with minimum 6-8 years of industrial experience in Pharmaceutical Process R&D or CRAMS or CRO set up (or) organic and peptide synthesis
Strong background in synthetic organic and peptide chemistry, characterization of compounds based on IR, NMR, Mass Spectra, Elemental analysis and other analysis
Ability to independently search literature, design, optimize and develop synthetic processes for any given APIs/ Target molecules
Hands on experience in process development of diverse chemical class of APIs/ NCEs on lab scale
Excellent troubleshooting skills in synthesis and purification of target compounds
Should possess good verbal and written communication skills.
Should possess good organizational, communication, and interpersonal skills
Additional Desired Preferences
Extensive knowledge on various types of organic reactions, peptide synthesis and practical experience in handling various chemicals/reagents
Track record of patents/ publications in synthetic organic chemistry/ process development
Should have exposure to GMP/GLP environment and documentation procedures. Have good practical, documentation & presentation Skills
Meticulous attention to detail, as well as outstanding critical thinking and problem-solving skills
Demonstrated ability to work both independently and as a member of a team, show initiative, solve problems, prioritize the activities, and meet deadlines.
USP provides you with the benefits you need to protect yourself and your family today and tomorrow. From company-paid time off, comprehensive healthcare options to retirement savings, you can have peace of mind that your personal and financial wellbeing is protected.
COVID-19 Vaccination Policy (will apply to the selected candidate(s) hired):
As a condition of employment with the United States Pharmacopeial Convention's (USP) duty to provide and maintain a workplace free of known hazards, all employees and contingent staff hired after July 1st, 2021, must be fully vaccinated unless a reasonable accommodation is approved. Your recruiter will advise accordingly.
USP is proud to be an equal employment opportunity employer (EEOE) and affirmative action employer. We are committed to creating an inclusive environment in all aspects of our work—from the standards we make to the partnerships and conversations we cultivate. An environment where every employee feels fully empowered and valued irrespective of, but not limited to, personality, race, ethnicity, physical and mental abilities, education, religion, gender identity and expression, life experience, sexual orientation, country of origin, regional differences, work experience, and family status. We are committed to working with and providing reasonable accommodation to individuals with disabilities.
Note: USP does not accept unsolicited resumes from 3rd party recruitment agencies and is not responsible for fees from recruiters or other agencies except under specific written agreement with USP.
Job Category Chemistry & Scientific Standards
Job Type Full-Time