U.S. Pharmacopeial Convention Jobs

Job Information

The U.S. Pharmacopeial Convention (USP) Scientist III, Synthetics in Hyderabad, India

Description

Summary of the Position

The role is engaged in the delivery of USP Reference Standard candidate materials (API Impurities) through development of cost-effective synthetic routes They carry literature search using scientific databases and works on design, planning and execution of synthesis of target molecules in mg to multigram/KG scale. They optimize key reactions and develops scalable process and develop control strategies using PAT. As project team member, ensures the completion of assigned tasks as per timelines, communicates with the team and update on the project progress. They are also responsible for making project reports and technology transfer documents. They should be adherent to QMS and lab safety guidelines. They should possess excellent organizational, communication, and interpersonal skills.

Roles and Responsibilities

  • Responsible for carrying out literature search and propose and design synthetic routes for target reference materials and for new target molecules respectively.

  • The candidate should be acquainted with all key name reactions, product identification and purification through various techniques such as crystallization, column chromatography and chemical purification of organic and peptide molecules

  • Responsible for the synthesis of the products at diverse scales (milligram to multigram)

  • Experience in handling large scale reactions.

  • Adept in trouble shooting problems encountered during the reaction sequence

  • Ability to work on more complicated and creative projects

  • Conversant with lab safety norms and quality management systems

  • General Material balance, Process Flow Diagrams (PFD), Recovery of solvents, Selection of equipment etc.,

  • Characterization of compounds based on IR, NMR, Mass Spectra, Elemental analysis etc.

  • To execute and completes the projects as per the timelines.

  • Ensuring that the availability of chemicals, equipment and glass wares etc. for the projects and forward the purchase requisitions.

  • Periodic check of the assigned equipment to ensure that equipment is in good condition.

  • To follow QMS of USP

  • Responsible for review the records and documents

  • Responsible to ensure the calibrations of the equipment as per the schedule

  • Maintenance of chemical inventory management system in the lab.

  • Responsible for maintenance of rejection folder according to synthetic works flow

Basic Qualifications

  • Scientist III – Ph.D (Synthetic Organic Chemistry) from a reputed group with minimum 0-2 years post-doctoral or industrial experience in organic and peptide synthesis

(Or) M Sc (Organic Chemistry) from a reputed university with minimum 7-8 years of industrial experience in Pharmaceutical Process R&D or CRAMS or CRO set up (or) organic and peptide synthesis

Strong background in synthetic organic and peptide chemistry, characterization of compounds based on IR, NMR, Mass Spectra, Elemental analysis and other analysis

  • Ability to independently search literature, design, optimize and develop synthetic processes for any given APIs/ Target molecules

  • Hands on experience in process development of diverse chemical class of APIs/ NCEs on lab scale

  • Excellent troubleshooting skills in synthesis and purification of target compounds

  • Should possess good verbal and written communication skills.

  • Should possess good organizational, communication, and interpersonal skills

Preferred Qualifications

  • Extensive knowledge on various types of organic reactions, peptide synthesis and practical experience in handling various chemicals/reagents

  • Track record of patents/ publications in synthetic organic chemistry/ process development

  • Should have exposure to GMP/GLP environment and documentation procedures. Have good practical, documentation & presentation Skills

  • Meticulous attention to detail, as well as outstanding critical thinking and problem-solving skills

  • Demonstrated ability to work both independently and as a member of a team, show initiative, solve problems, prioritize the activities, and meet deadlines.

Supervisory Responsibilities

Not Applicable

Benefits

USP provides you with the benefits you need to protect yourself and your family today and tomorrow. From company-paid time off, comprehensive healthcare options to retirement savings, you can have peace of mind that your personal and financial wellbeing are protected.

About USP

The U.S. Pharmacopeial Convention (USP) USP is an independent scientific organization that collaborates with the world's top experts in health and science to develop quality standards for medicines, dietary supplements, and food ingredients. USP brings together more than 1,100 talented professionals across five global locations to deliver its mission to strengthen the supply of safe quality medicines and supplements worldwide. USP is proud to be an equal employment opportunity employer (EEOE) and affirmative action employer. Employment selection and related decisions are made without regard to sex, race, age, disability, religion, national origin, color, veteran status, sexual orientation, gender identity or any other protected class. We are committed to working with and providing reasonable accommodation to individuals with disabilities. USP does not accept unsolicited resumes from 3rd party recruitment agencies and is not responsible for fees from recruiters or other agencies except under specific written agreement with USP.

Job Category Chemistry & Scientific Standards

Job Type Full-Time

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